Saturday, December 16, 2023

Let's write more about Henrietta Lacks

The donation of Henrietta Lacks' cells began what was the first, and, for many years, the only human cell line able to reproduce indefinitely. Her cells, known as HeLa cells for Henrietta Lacks, remain a remarkably durable and prolific line of cells used in research around the world.
HeLa cells were the first discovered immortalized human cell line (cells that can be continuously grown) in 1951 and have since become one of the most important cell lines in medical research.

Henrietta Lacks Family, Thermo Fisher Settle Cell Use Lawsuit
The settlement with the Massachusetts-based company came more than 70 years after doctors took Lacks' cancer cells without her consent.  Echo report by Megan VerHeist published the Dundalk (Maryland) Patch.

BALTIMORE, MD — Lawyers for the descendants of Henrietta Lacks, a Black woman whose cervical cancer cells were taken without her consent more than 70 years ago, said a settlement had been reached with the biotechnology company they sued in 2021.
What many people using this cancer cell line did not know, was that these cells were unknowingly harvested from a 31-year-old African-American woman being treated for cervical cancer at Johns Hopkins Hospital. This woman’s name was Henrietta Lacks.

The settlement with Massachusetts-based Thermo Fisher came after Lacks' family accused the company of using Lacks' cells for "unjust enrichment" and accused its leaders of reaping billions of dollars from a racist medical system.

The family did not ask for specific monetary damages in the lawsuit, according to reports.


The settlement came after closed-door negotiations that lasted all day Monday inside the federal courthouse in Baltimore. Several
members of the Lacks family were in on the talks.
Attorney Ben Crump, who represents the Lacks family, announced the settlement late Monday. He said the terms of the agreement are confidential.

"The parties are pleased that they were able to find a way to resolve this matter outside of Court and will have no further comment about the settlement," Crump said in a statement.

The lawsuit against biotechnology company Thermo Fisher Scientific claimed Lacks' cells were taken while she was receiving treatment at Johns Hopkins in 1951. Lacks, who was from Baltimore County, died at 31 and was buried in an unmarked grave. A poor tobacco farmer from southern Virginia, she was raising five children when doctors discovered a tumor in her cervix and saved a sample of her cancer cells collected during a biopsy.

The cells taken from Lacks became the first human cells to be successfully cloned, according to a report from The Associated Press. Now called HeLa cells, they have enabled numerous scientific and medical innovations, including the development of the polio vaccine, genetic mapping, and even COVID-19 vaccines.

HeLa cells were discovered to have unique properties. While most cell samples died shortly after being removed from the body, her cells survived and thrived in laboratories. This exceptional quality made it possible to cultivate her cells indefinitely — they became known as the first immortalized human cell line — making it possible for scientists anywhere to reproduce studies using identical cells.

The discovery and the science involved were detailed in a 2010 bestselling book, "The Immortal Life of Henrietta Lacks." Oprah Winfrey portrayed her daughter in an HBO movie based on the book.

Johns Hopkins said it never sold or profited from the cell lines, but many companies have patented ways of using them.

In their complaint, Lacks' grandchildren and other descendants argued that her treatment illustrates a much larger issue that persists into the present day: racism inside the American medical system.

"The exploitation of Henrietta Lacks represents the unfortunately common struggle experienced by Black people throughout history," the complaint reads. "Too often, the history of medical experimentation in the United States has been the history of medical racism."

Thermo Fisher previously argued the case should be dismissed because it was filed after the statute of limitations expired, but attorneys for the family said that shouldn't apply because the company is continuously benefitting from the cells.

The Associated Press contributed to this report.

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Tuesday, September 19, 2023

Let's write about Baltimore native John Waters on the Hollywood Walk of Fame

Baltimore's John Waters Receives Star On Hollywood Walk of Fame

In an interview with Baltimore Fishbowl last year, Waters said he was thrilled to be chosen as an honoree. “I am really excited about it,” he added. “Are you kidding? I wish my parents were alive.”

John Waters Walk of Fame.jpg

John Waters poses with his new star during a ceremony on the Hollywood Walk of Fame Monday, Sept. 18, 2023, in Los Angeles. Waters, a Baltimore native, has directed more than a dozen movies. (AP Photo/Chris Pizzello)

Known for his pencil-thin mustache, Waters grew up in Baltimore in the 1950s. According to his IMDb profile, he began making silent films in the mid-'60s and screened them in rented Baltimore church halls to underground audiences.  His "big break" came with the 1972 release of "Pink Flamingos," a movie about an eccentric woman named Divine and her unusual family competing with a Baltimore couple to be named "the filthiest people alive."

His Hollywood crossover success came with 1988's cult classic, "Hairspray," a movie Waters directed and wrote.

Several of Waters' friends and collaborators shared their thoughts about the filmmaker during the ceremony, including Mink Stole, who has appeared in all 12 of Waters' features.  "I don't know how John's brain works. I don't know how he comes with with characters like the Egg Lady, who lives in a crib in her underwear," Stole said. "What I do know is that John is brilliant, he is decent — unfailingly decent — and he is the hardest working man in show business. I am proud of the work that I've done with John but I have to tell you that I am far more proud that for well over half a century he has been my friend."

Ricki Lake, who appeared in five of Waters' films, including 1988's "Hairspray," shared a letter she wrote after production of the film wrapped — revealing how Waters' off-color sensibilities remained baked in to the film despite its PG rating.

The then 18-year-old Lake, who starred as a "pleasantly plump" teen dancer on an anti-racial segregation crusade, wrote that working on the film instilled her with self-confidence despite the strange situations production put her in.

"So what if 1. I had to remain fat for two months straight. 2. Wear live roaches on my back, not to mention rats. 3. Be smashed in the face with a huge ball. 4. Be hoisted in the air like an immobile Mack truck. 5. Lick a TV screen as if it was licking me back. And 6. Respond to the name Orca — So what, I'm me!," Lake said.

Waters' star is located outside the Larry Edmunds Bookshop, at 6844 Hollywood Blvd., a long-running film-history focused store.
"I've been coming here for half a century. It's still my favorite spot on Hollywood Boulevard," Waters said.
And he has a wish for the pedestrians strolling the Walk of Fame and passing by his star.
"I hope the most desperate showbiz rejects walk over me here and feel some sort of respect and strength. The dreams on this magic boulevard will never wash away the gutter of my gratitude," he said.

The Academy Museum's exhibition, "John Waters: Pope of Trash," runs through Aug. 4, 2024. It includes costumes, set decorations, props, handwritten scripts, posters, concept designs, correspondence, scrapbooks, photographs and film clips


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